The predecessor of the Hsinchu District Prosecutors Office, during the period of Japanese occupation, was the branch of Taiwan Taipei District Prosecutorial Office (臺灣臺北地方法院新竹支部檢察局), which administered one city and eight counties. In 1937, the branch became the Taiwan Hsinchu District Prosecutorial Office (臺灣新竹地方法院檢察局) which governed an area which included present Hsinchu County, Hsinchu City, Taoyuan and Miaoli areas. At that time, the Taiwan Hsinchu District Prosecutorial Office was one of the most important government offices in the Hsinchu area. In 1945(the 34th year of the Republic of China), Taiwan recovered from the Japanese occupation, and the Taiwan Hsinchu District Prosecutorial Office was renamed as the Taiwan Hsinchu District Prosecutors Office (臺灣新竹地方法院檢察處) , and retained its original jurisdiction. In 1968(the 57th year of the Republic of China), for the convenience of Miaoli's residents, a branch office was established in Miaoli. Over time, since the development of its industry and commerce, Taoyuan increased in population. As a result, in 1973, the Taiwan Taoyuan District prosecutors Office was founded and took charge of the Taoyuan area. In 1997, the Miaoli District Prosecutors Office took charge of the Miaoli area. Presently, the Hsinchu Prosecutors Office covers only Hsinchu County and Hsinchu City.

On December 24, 1989, in accordance with the amendments to the Court Organization Act, the "Taiwan Hsinchu District Court Prosecutor's Office" was renamed as the "Taiwan Hsinchu District Court Prosecutors Office," and the head of the agency, previously known as the "Chief Prosecutor," was also renamed as the "Prosecutor General." The amendments to Article 114-2 of the Court Organization Act and Article 5 of the Ministry of Justice Organization Act were announced by the President on May 23, 2018, and took effect on May 25, 2018. As a result, the names of the prosecutorial agencies were depersonalized, and the District Court Prosecutors Offices were renamed as District Prosecutors Offices, with this office being renamed as the "Taiwan Hsinchu District Prosecutors Office."

Historical Development Process：
Predecessor：Established during the Japanese occupation period in the 28th year of the Meiji era as the "Hsinchu Branch of the Taiwan Governor-General's Court."
Year 9 of the Republic of China：Established the "Hsinchu Branch Prosecutor's Office of the Taipei District Court."
Year 26 of the Republic of China：Reorganized as the "Prosecutor's Office of the Hsinchu District Court of Taiwan."
Year 34 of the Republic of China：After the recovery, renamed the "Prosecutor's Office of the Hsinchu District Court of Taiwan."
December 24, Year 78 of the Republic of China：Renamed the "Hsinchu District Prosecutor's Office of Taiwan."
Year 93 of the Republic of China：Approved by the Ministry of Justice to obtain land for relocation without compensation.
December of Year 97 of the Republic of China：Acquired land in the Ziqiang section, Zhubei City, Hsinchu County, without compensation for the construction.
March of Year 101 of the Republic of China：Groundbreaking for the construction of the office building.
April of Year 103 of the Republic of China：Completion of the new office building.
February of Year 104 of the Republic of China：The new office building was inaugurated and has been in use since then.
Year 107 of the Republic of China：In accordance with the "Court Organization Act," renamed the "Hsinchu District Prosecutor's Office of Taiwan."